Weight Loss Made Easy!

BioOptimal has partnered with CareGLP by CareValidate

to address weight loss and obesity-related health challenges.

To learn more or make a purchase

Click here

GLP-1 Overview

Glucagon-like peptide 1 is a type of hormone known as an incretin. Incretins stimulates insulin secretion in response to food intake, among other effects.

In addition to stimulating insulin secretion, GLP-1 slows gastric emptying, inhibits glucagon release, and acts in the brain to decrease appetite and food intake.

GLP-1 Effects in the Body

GLP-1 Indications

Adults: BMI ≥30 or BMI ≥27 with:

  • Type 2 Diabetes or pre-diabetes
  • Hypertension
  • Cardiovascular Diseases
  • Dyslipidemia (high cholesterol or
    triglycerides)
  • Polycystic ovary syndrome
  • Osteoarthritis
  • Obstructive Sleep Apnea
  • Non-alcoholic Fatty Liver Disease
  • Metabolic Syndrome

GLP-1 Contraindications

Black Box Warning

  • Medullary thyroid carcinoma (MTC) or family history
  • Multiple Endocrine Neoplasia syndrome type 2
  • Serious allergic reaction to semaglutide or tirzepatide

Others

  • Active cancer
  • Active drug or alcohol misuse
  • Eating disorders
  • Bipolar disorder
  • Schizophrenia
  • Pancreatitis